Presentamos el caso de una paciente de 44 años estudiada por amenorrea e hiperprolactinemia. No refería galactorrea, cefalea ni alteraciones en la visión. HIPERPROLACTINEMIA Y PROLACTINOMA. MP Diagnóstico específico: PRL se deben medir en todo paciente con hipogonadismo o. A hiperprolactinemia causa hipogonadismo hipogonadotrófico principalmente por inibir a secreção pulsátil do GnRH, além de inibir diretamente a.

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[Current diagnosis and treatment of hyperprolactinemia].

A comparison of cabergoline and bromocriptine in the treatment of hyperprolactinemic amenorrhea. De los estudios no aleatorizados incluidos, los tres corresponden a cohortes retrospectivas.

A PRL pode ser classificada nas seguintes isoformas, de acordo com o peso molecular: The primary treatment of prolactinomas is pharmacological with dopamine agonists such as cabergoline. A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer. Quality huperprolactinemia life is decreased in female patients treated for microprolactinoma.

A paciente deve ser monitorada clinicamente a cada trimestre. Orphanet J Rare Dis. Radiotherapy for prolactin-secreting pituitary tumors.


Do the limits of serum prolactin in disconnection hyperprolactinaemia need re-definition? Diagnosis and treatment of hyperprolactinemia: Emotional aspects of hyperprolactinemia.

їCabergolina o bromocriptina para el prolactinoma? – Medwave

Asymptomatic hyperprolactinaemia and prolactinoma in the general population-mass screening by paired assays of serum prolactin. However, it is not clear if this translates into clinical benefits. Prolactin receptor gene expression and immunolocalization of the prolactin receptor in human luteinized granulose cells. Pituitary tumors in pregnancy. Kluwer Academic Publishers; Human macroprolactin displays hiperprolqctinemia biological activity via its homologous receptor in a new sensitive bioassay.

Twenty-four hour secretory patterns of prolactin in women. BMI and metabolic profile in patients with prolactinoma before and after treatment with dopamine agonists. Prolactin; hyperprolactinemia; prolactinoma; pseudoprolactinoma; pituitary adenoma; neurosurgery; macroprolactina; dopamine agonist. High prolactin levels may be missed by immunoradiometric assay in patients with macroprolactinomas.

Hyperprolactinemia causes hypogonadism, menstrual irregularities or amenorrhea in women, low serum testosterone levels in men, and infertility and sexual dysfunction in both men and women.

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Temozolomide in the management of dopamine agonist-resistant prolactinomas. J Clin Endocrinol Metab.

Primary medical therapy of micro- and macroprolactinomas in men. Quality of life in women with microprolactinoma treated with dopamine agonists. It is not clear whether cabergoline is also more effective with respect to tumor growth because the certainty of the evidence is very low.


Once physiological causes such as pregnancy, systemic disorders such as primary hypothyroidism and the use of drugs with dopamine antagonistic actions such as metochlopramide have been ruled out, the most common cause of hyperprolactinemia is a Hiperprolachinemia pituitary adenoma or prolactinoma.

Mah PM, Webster J. Patterns of visual loss associated with pituitary macroadenomas.


Resistance to cabergoline as compared with bromocriptine in hyperprolactinemia: N Engl J Med. Outcome of cabergoline treatment in men with prolactinoma: Colao A, Loche S.

Prolactinomas resistant to standard doses of cabergoline: Nos macroprolactinomas, o manejo deve ser individualizado.